Publications

The research conducted at CQM is divided between two groups: Materials and Natural Products and it complies with the highest standards of quality which have lead to many publications in International Journals, books and chapters.

Facilities

CQM has ten specialised research labs which are accessible to all members.

Our equipment

Team

The CQM team has over 50 researchers from multiple nationalities across many fields. The Scientific Commission is made up by the most experienced senior researchers and they are responsible for managing CQM's activities.

Get to know our team!

Funding Agencies

Ongoing Projects

Completed projects

- 2020
- - BlueHuman - BLUE (marine) biotechnology as a platform for innovation in Atlantic Area towards the smart and sustainable growth of Europe on HUMAN’s health and well-being (EAPA_151/2016). Funded by: Atlantic Area INTERREG (01/01/2018 - 31/12/2020). Main contractor: Universidade do Minho. Total funds: € 1 892 901. CQM (Team member): € 99 968.
- 2019
- - ECOFIBRAS - Valorização ecosustentável de espécies vegetais invasoras da Macaronésia para a obtenção de fibras industriais (MAC/4.6D/040). Funded by: Mac 14-20 (01/01/2017 - 31/12/2019). Main contractor: Universidade de Las Palmas de Gran Canária. Total funds: € 953 607.48. CQM (Team member): € 151 022.55.
  - BIOTRANSFER2 - Transferência da investigação biotecnologica orientada à rentabilidade empresarial e à mobilização de fluxos de negócio (MAC/1.1b/042). Funded by: Mac 14-20 (01/01/2017 - 31/12/2019). Main contractor: Cabildo Inslular de Tenerife. Total funds: € 801 473.17. CQM (Team member): € 57 489.94.
  - Centro de Química da Madeira (PEst-UID/QUI/00674/2019). Funded by: State Budget (01/01/2019 - 31/12/2019). Total funds: € 120 273.
  - NCDs-CAPomics - Combining volatomics, multivariate statistical analysis and optical fibre sensor as a promising, innovative and integrating approach for ncds diagnostics. Case study of cancer and neurodegenerative diseases (INNO INDIGO IPP2 NCDs-CAPomics). Funded by: INNO INDIGO (01/07/2016 - 01/02/2019). Total funds: € 199 066.
  - MarineBlueRefine (M1420-01-0247-FEDER-000006). Funded by: Madeira 14-20 (01/02/2017 - 31/01/2019). Main contractor: Madebiotech - CR&D, S.A.. Host institution: UMa (CQM). Total funds: € 1 000 000. CQM (Team member): € 452 644.05.
- 2018
- - PROEQUIPRAM - Reforço do Investimento em Equipamentos e Infraestruturas Científicas na RAM (M1420-01-0145-FEDER-000008). Funded by: Madeira 14-20 (01/07/2017 - 31/12/2018). Total funds: € 382 500.
  - CQM - Centro de Química da Madeira – Financiamento plurianual (PEst-UID/QUI/00674/2013). Funded by: State Budget (01/01/2015 - 31/12/2018). Total funds: € 482 892.
  - BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke (PTDC/CTM-NAN/3547/2014). Funded by: Fundação para a Ciência e Tecnologia (01/01/2015 - 31/12/2018). Main contractor: Instituto Nacional de Engenharia Biomédica (INEB, Porto). Total funds: € 195 256. CQM (Team member): € 10 080.
- 2017
- - Cyted Red 214RT0482 - Desarrollo de una vacuna frente a VIH: estudio de los cambios en la biología de células dendríticas humanas tras interacción con distintos sistema de liberación de péptidos de VIH (vihvacd) (Cyted Red 214RT0482). Funded by: CYTED (01/01/2014 - 31/12/2017). Main contractor: Hospital General Universitario Gregorio Marañón. Total funds: € 100 000. CQM (Team member): € 22 000.
- 2015
- - AVC-MaC-CV - Evaluation of the health protective effects of polyphenols-rich diets in the evolution of Cardiovascular biomarkers (MAC/3/M251). Funded by: MAC 2007-2013 (06/06/2014 - 31/12/2015). Total funds: € 154 514. CQM (Team member): € 150 000.
  - Self-assembled nanoparticles based on PEG-PLA-dendrimer building blocks for dual gene/drug delivery (PTDC/CTM-NAN/116788/2010). Funded by: FCT (01/01/2012 - 31/12/2015). Main contractor: Universidade da Madeira. Total funds: € 156 808. CQM (Project Leader): € 156 808.
  - DENDIMAGE - Development of Novel Dendrimer-Based Nanoparticles for Dual Mode Computed Tomography and Magnetic Resonance Imaging of Tumors (PTDC/CTM-NAN/1748/2012). Funded by: FCT (01/01/2013 - 01/01/2015). Main contractor: Universidade da Madeira. Total funds: € 197 616. CQM (Project Leader): € 197 616.
- 2014
- - DENDRIMAT - New materials for drug/gene delivery based on the self-assembly of dendrimer-chitosan-ssDNA (PTDC/CTM-NAN/112428/2009). Funded by: FCT (01/01/2011 - 01/01/2014). Main contractor: Universidade da Madeira. Total funds: € 151 251. CQM (Project Leader): € 151 251.
- 2013
- - VinSaudeMAC - Evaluation of the biological effects of red wines on the prevention of atherosclerotic, oncologic and neurologic diseases (MAC/1/M105). Funded by: Interreg IIIB (01/01/2009 - 31/12/2013). Total funds: € 617 541. CQM (Project Leader): € 267 949.
- 2011
- - FUNCMETAL - Functionalized Metallodendrimers Based on 2,4,6-tri-substituted-1,3,5-triazine Core Derivatives (PTDC/QUI/64202/2006). Funded by: Fundação para a Ciência e Tecnologia (01/01/2008 - 31/12/2011). Total funds: € 101 200.
- 2010
- - DENDRALGENE - Design of New Gene Delivery Vectors Based on Dendrimers, Alginate and the RGD Sequence for Bone Tissue Engineering (PTDC/SAU-BEB/71161/2006). Funded by: Fundação para a Ciência e Tecnologia (01/01/2007 - 31/12/2010). Total funds: € 175 000.
- 2008
- - BIOPOLIS - Building an European Bioregion (Interreg IIIB 05/MAC/2.3/C14). Funded by: FEDER INTERREG IIIB (01/01/2006 - 31/12/2008). Host institution: Fundación Canaria de Investigación y Salud. Total funds: € 708 000. CQM (Team member): € 176.
  - RNEM - Rede Nacional de Espectrometria de Massa (REDE/1508/REM/2005). Funded by: Fundação para a Ciência e Tecnologia (01/01/2006 - 31/12/2008). Total funds: € 3 300 000. CQM (Team member): € 167 000.
  - ANTIVINMAC - Determination of Antioxidant Potential, Amino Acids and Biogenic Amines in Wines from Canárias, Azores and Madeira (Interreg IIIB 05/MAC/2.3/M28). Funded by: FEDER INTERREG IIIB (01/01/2005 - 31/12/2008). Total funds: € 304 353.
- 2007
- - PTNMR - Rede Nacional de Ressonância Magnética Nuclear (REDE/1517/RMN/2005). Funded by: Fundação para a Ciência e Tecnologia (01/01/2006 - 31/12/2007). Total funds: € 6 500 000. CQM (Team member): € 278 179.
  - Novel Polarised Molecular Wires Based on Transition Metal Complexes of Di(4-pyridyl)heterocycles Spacers Bridging Ligands (POCTI/CTM/41495/2001). Funded by: Fundação para a Ciência e Tecnologia (01/04/2004 - 31/03/2007). Total funds: € 87 510.
- 2006
- - CLAYCATS - Modified Porto Santo Clays as Catalysts for Liquid Phase Organic Reactions (POCTI/CTM/47619/2002). Funded by: Fundação para a Ciência e Tecnologia (01/01/2003 - 31/12/2006). Total funds: € 72 000.
  - CARVINMAC - Caracterização dos vinhos elaborados com castas autóctones da Madeira, Açores e Canárias (MAC/2.3/M51). Funded by: FEDER INTERREG IIIB (01/01/2000 - 31/12/2006). Total funds: € 520 000. CQM (Team member): € 210 000.
- 2005
- - Sistemas tridimensionais de colagénio tipo I, proteoglicanos e factores de crescimento (POCTI/FCB/33620/1999). Funded by: Fundação para a Ciência e Tecnologia (01/01/2003 - 31/12/2005). Total funds: € 64 843.73.
  - Synthesis and Study of New Organometallic Dendrimers for Nonlinear Applications (POCTI/QUI/41814/2001). Funded by: Fundação para a Ciência e Tecnologia (01/01/2003 - 31/12/2005). Total funds: € 72 300.

Get to know our team!

- Articles in international journals
- Articles in international journals without Impact Factor
- Books
- Book chapters
- International proceedings
- Thesis
- Activity Report

Articles in international journals

- 2021
- - 11. Chen, Y. ; Jia, Z. ; Shafiq, M.; Xie, X. ; Xiao, X. ; Castro, R.; Rodrigues, J.; Wu, J.; Zhou, Guangdong ; Mo, X. Gas foaming of electrospun poly(L-lactide-co-caprolactone)/silk fibroin nanofiber scaffolds to promote cellular infiltration and tissue regeneration . Colloid Surf. B-Biointerfaces 2021, 201, 111637-. (IF: 4.389) Q1 (Biotechnology)
  - 10. Gonçalves, J. L. J.; Alves, V. L. G.; J. Aguiar; Caldeira, M. ; Teixeira, H. ; Câmara, J.S. Structure Assignment of Seized Products Containing Cathinone Derivatives Using High Resolution Analytical Techniques . Metabolites 2021, 11, 144-. (IF: 4.097) Q2 (Biochemistry)
  - 9. Qiu, J.; Chen, L.; Zhan, M.; Laurent, R.; Bignon, J.; Mignani, S. M.; Shi, X.; Caminade, A-M.; Majoral, J-P. Facile Synthesis of Amphiphilic Fluorescent Phosphorus Dendron-Based Micelles as Antiproliferative Agents: First Investigations . Bioconjugate Chem. 2021, 32, 339-349. (IF: 4.031) Q1 (Bioengeneering)
  - 8. Mignani, S. M.; Shi, X.; Zablocka, M.; Majoral, J-P. Dendritic Macromolecular Architectures: Dendrimer-Based Polyion Complex Micelles . Biomacromolecules 2021, 22, 262-274. (IF: 6.092) Q1 (Bioengeneering)
  - 7. Zhu, B.; Wu, X.; Rodrigues, J. M. C.; Hu, X.; Sheng, R.; Bao, G.-M. A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells . Spectrochim Acta A 2021, 246, 118953-. (IF: 3.232) Q2 (Analytical Chemistry)
  - 6. Su, X.; Wang, L.; Xie, J.; Liu, X. ; Tomás, H. Cyclotriphosphazene-based Derivatives for Antibacterial Applications: An Update on Recent Advances . Curr. Org. Chem. 2021, 25, 301-314. (IF: 1.933) Q3 (Organic Chemestry )
  - 5. Jia, L.; Li, X.; Liu, H.; Xia, J.; Shi, X.; Shen, M. Ultrasound-enhanced precision tumor theranostics using cell membrane-coated and pH-responsive nanoclusters assembled from ultrasmall iron oxide nanoparticles . Nano Today 2021, 36, 101022-. (IF: 16.907) Q1 (Materials Science)
  - 4. Nunes, N. S. H.; Popović, I.; Abreu, E. A. S.; Maciel, D.; Rodrigues, J. M. C.; Soto, J.; Algarra, M.; Petkovic, M. Detection of Ru potential metallodrug in human urine by MALDI-TOF mass spectrometry: Validation and options to enhance the sensitivity . Talanta 2021, 222, 121551-. (IF: 5.339) Q1 (Analytical Chemistry)
  - 3. Perestrelo, R. M. d. S.; Petkovic, M.; Silva, C. G. S. L. Analytical Platforms for the Determination of Phospholipid Turnover in Breast Cancer Tissue: Role of Phospholipase Activity in Breast Cancer Development . Metabolites 2021, 11, 32-. (IF: 4.097) Q2 (Biochemistry)
  - 2. Mignani, S. M.; Shi, X.; Karpus, A.; Majoral, J-P. Non-invasive intranasal administration route directly to the brain using dendrimer nanoplatforms: An opportunity to develop new CNS drugs . Eur. J. Med. Chem. 2021, 209, 112905-. (IF: 5.572) Q1 (Drug Discovery)
  - 1. Mignani, S. M.; Shi, X.; Steinmetz, A.; Majoral, J-P. Multivalent Copper(II)-Conjugated Phosphorus Dendrimers with Noteworthy In Vitro and In Vivo Antitumor Activities: A Concise Overview . Mol. Pharm. 2021, , 65-73. (IF: 4.321) Q1 (Drug Discovery)
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- 2004

Articles in international journals without Impact Factor

- 2020
- - 3. Jeevanandam, J.; Banerjee, S.; Paul, R. Challenges and Opportunities to Develop Diagnostics and Therapeutic Interventions for Severe Acute Respiratory Syndrome- Corona Virus 2 (SARS-COV-2) . J. Biomed. Res. Env,. Sci. 2020, 1, 219-232.
  - 2. Li, J.; Shen, M.; Shi, X. Poly(amidoamine) Dendrimer-Gold Nanohybrids in Cancer Gene Therapy: A Concise Overview . ACS Applied Bio Materials 2020, 3, 5590-5605.
  - 1. Perestrelo, R. M. d. S.; Silva, C. G. S. L.; Gonçalves, C.; Mariangie M. Castillo ; Câmara, J.S. An approach of the Madeira Wine Chemistry . Beverages 2020, 6, 12-.
- 2019
- 2018
- 2017
- 2016

Books

- 2012
- - 1. Pereira, J. Deciphering the role of Yap4 phosphorylation under stress conditions. Pereira, J.; Lambert Academic Publishing: New York, 2012.

Book chapters

- 2020
- - 1. Sheng, R. Steroid-Based Supramolecular Systems and their Biomedical Applications: Biomolecular Recognition and Transportation . In Chemistry and Biological Activity of SteroidsSalvador, J. A. R.; IntechOpen: London, 2020; pp 1-19.
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International proceedings

- 2019
- - 6. Andrade, B.; Pereira, J. A. M.; Câmara, J.S. Analysis of skin volatiles using a membrane-SPME/GC-MS approach to unveil putative biomarkers for neurodegenerative diseases . Presented at 11º Encontro Nacional de Cromatografia, Caparica, Portugal, 2019.
  - 5. Gonçalves, J. L.; Alves, V. L.; Calderia, M. J.; Teixiera, H. M. Chemical characterization of new psychoactive substances belonging to the class of synthetic cathinones in seized materials in Portugal . Presented at 11º Encontro Nacional de Cromatografia, Caparica, Portugal, 2019.
  - 4. Priscilla, P.-F.; Figueira, J.; Batista, M.; Berenguer, C.; Pereira, J. A. M.; Máximo, V.; Câmara, J.S. Selection of the best urine sampling period based on the volatomic profile . Presented at 11º Encontro Nacional de Cromatografia, Caparica, Portugal, 2019.
  - 3. Alves, V. L.; Gonçalves, J. L.; Calderia, M. J.; Teixiera, H. M.; Câmara, J.S. Screening of ‘Spice’ herbal mixtures using GC-MS and NMR as complementary techniques . Presented at 11º Encontro Nacional de Cromatografia, Caparica, Portugal, 2019.
  - 2. Aguiar, J.; Gonçalves, J. L.; Câmara, J.S. Evaluation of bioactive potential and volatomic pattern of foods from vegetable origin . Presented at 11º Encontro Nacional de Cromatografia, Caparica, Portugal, 2019.
  - 1. Freitas, J.; Silva, P.; Vaz-Pires, P.; Câmara, J.S. Development of a SPME/GC-MS method based on Quality by Design approach, for evaluation of fish deterioration progress through TMA and DMA quantification . Presented at 11º Encontro Nacional de Cromatografia, Caparica, Portugal, 2019.
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Thesis

- 2019
- - 9. Costa, F. H. O. M. P. Nanopartículas de colagénio para terapias da cartilagem baseadas em recursos marinhos . M. Sc. Thesis, Master Degree in Applied Biochemistry, University of Madeira, Portugal, 2019.
  - 8. Vatansever, S. Development of new nanocomposites for waste water cleaning . M. Sc. Thesis, Master Degree in Nanochemistry and Nanomaterials, University of Madeira, Portugal, 2019.
  - 7. Zou, Y. Formation of functional polyetheylenimine-based nanogels for tumor MR imaging and chemotherapy . M. Sc. Thesis, Master Degree in Nanochemistry and Nanomaterials, University of Madeira, Portugal, 2019.
  - 6. Silva, C. L. Non-invasive, Innovative and Promising Strategy for Breast Cancer Diagnosis Based on Metabolomic Profile of Urine, Cancer Cell Lines and Tissue . Ph. D. Thesis, Ph.D. Degree in Chemistry, University of Madeira, Portugal, 2019.
  - 5. Santos, M. P. Exploring the potential sorbent capacity of iron nanostructures to isolate urinary endogenous metabolites . M. Sc. Thesis, Master Degree in Nanochemistry and Nanomaterials, University of Madeira, Portugal, 2019.
  - 4. Reis, D. C. F. Development of a methodology based on QuEChERS-dSPE/UHPLC-PDA to quantify pesticide residues in potatoes . M. Sc. Thesis, Master Degree in Applied Biochemistry, University of Madeira, Portugal, 2019.
  - 3. Pataca, J. K. G. USAMET/UHPLC-FLR como nova abordagem analítica para a quantificação de aminas biogénicas em tunídeos . M. Sc. Thesis, Master Degree in Applied Biochemistry, University of Madeira, Portugal, 2019.
  - 2. Tavares, G. M. F. Development and characterization of electrochemical sensors based on PAMAM dendrimers and citrate-stabilized gold nanoparticles . M. Sc. Thesis, Master Degree in Nanochemistry and Nanomaterials, University of Madeira, Portugal, 2019.
  - 1. Fernandes, Duarte From copper-based nanoparticles to carbon-based dots . M. Sc. Thesis, Master Degree in Nanochemistry and Nanomaterials, University of Madeira, Portugal, 2019.
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Activity Report

- 2015
- - 1. Centro de Química da Madeira CQM Activity Report 2014. 2015.
- 2014
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Publications

Cells being seeded in a Petri dish.

Although CQM's Future's Lab is stillunder construction, the work developed here will focus on microbiology and molecular biology.

Publications

Facilities

Team

Funding Agencies

Completed projects

Articles in international journals

Articles in international journals without Impact Factor

Books

Book chapters

International proceedings

Thesis

Activity Report

Publications

Future's Lab

Subcategories

Publications

Facilities

Equipment

Funding and Projects

Networks

Partnerships