25 noticias 251203 smignani

We are pleased to announce the next CQM Seminar titled "Bench-to-bedside translation of nanoparticles in oncology: Dendrimers case studies, reality or utopia?" with Professor Serge Mignani, senior researcher at CQM and at Centre d’Études et de Recherche sur le Médicament de Normandie & Argobio Studio, Paris (France). This seminar will take place on the 03rd of December 2025 at the conference room 0.57, Campus of Penteada, University of Madeira, starting at 15:00.

Space is limited, so please be sure to complete your registration as soon as possible.

Abstract:
Cancer is the most dangerous disease in the world in terms of mortality and lack of effective treatment. Research on cancer treatment is still active and of great social importance. Since 1930, chemotherapeutics have been used to treat cancer. However, such conventional therapies are associated with pain, side effects, and a lack of targeting. Nanomedicines are an emerging alternative due to their targeting, bioavailability, and low toxicity. Among the numerous nanomedicine formulations, dendrimers have emerged as original, efficient, carefully assembled, hyperbranched, polymeric nanoparticles based on synthetic monomers. Nanotechnology has made a significant impact on the delivery of drugs, as well as through their development as drugs themselves. Dendrimers are used either as nanocarriers of drugs or as drugs themselves. The purpose of this presentation is to analyze the different strategies involved in the development, application, and impact of dendrimers as nanodrugs as well as nanocarriers. We will analyze the clinical translation process of dendrimers and the main challenges. Also, we will examine a selection of nanoparticles that use multifunctional elements and demonstrate clinical multifunctionality, and we will extend these principles to applications in dendrimer nanomedicine design. Finally, for practical consideration, the concepts of vertical and diagonal translation will be discussed as potential strategies to facilitate dendrimer development.


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Limited seats available